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浜轰綋鑲″渚х毊绁炵粡瑙e墫瀛﹀拰瓒呭0鎺㈡煡

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鎽?nbsp;   瑕侊細銆€鐩殑 鎰熻寮傚父鎬ц偂鐥?MP)甯哥敱鑲″渚х毊绁炵粡(LFCN)鐨勬満姊板祵鍘嬪紩璧凤紝閫氬父鍙戠敓鍦ㄨ偂澶栦晶鐨缁忚蛋琛岃嚦楂傚墠涓婃鐨勯儴浣嶃€侻P鏈€浣虫墜鏈不鐤楁柟娉曟湁寰呯‘瀹氾紝閮ㄥ垎鍘熷洜鏄疞FCN鍛ㄥ洿绛嬭啘骞抽潰鐨勭簿缁嗙粨鏋勫皻鏈槓鏄庛€傛湰鐮旂┒鐨勭洰鐨勬槸鍒╃敤鐢熺墿濉戝寲鍜岃秴澹扮‘瀹歀FCN鍦ㄩ珎鍓嶄笂妫橀檮杩戠殑绛嬭啘缁撴瀯銆傛柟娉?閫夋嫨11鍏峰案浣?6鍚嶅コ鎬э紝5鍚嶇敺鎬э紝38锝?7宀?鍒朵綔钖勫眰鐢熺墿濉戝寲鍒囩墖銆傚34鍚嶅仴搴峰織鎰胯€?19鍚嶅コ鎬э紝15鍚嶇敺鎬э紝20锝?2宀?杩涜LFCN瓒呭0璇勪及銆傜粨鏋?LFCN鍦ㄨ吂鍐呮枩鑲岀瓔鑶滅氦缁村拰楂傜瓔鑶滀箣闂村嚭楠ㄧ泦锛岀劧鍚庡湪缂濆尃鑲岃〃闈㈠拰浣嶄簬楂傚墠涓婃(ASIS)涓嬫柟鐨勯様绛嬭啘寮犺倢涔嬮棿璧拌銆傚湪缂濆尃鑲屽拰闃旂瓔鑶滃紶鑲屼箣闂达紝LFCN璧拌鍦ㄧ嫭绔嬪皝闂殑绛嬭啘闉樹腑銆傜粨璁?LFCN鍦ㄩ珎鍓嶄笂妫樺浣嶄簬鑵瑰唴鏂滆倢鑵辫啘鍐呫€侺FCN鍦ㄧ紳鍖犺倢琛ㄩ潰鍙婂渚ц蛋琛岃嚦澶ц吙鍓嶅渚у尯鍩熴€傝秴澹板畾浣峀FCN鏈夊姪浜庡绉戞墜鏈€?/span>

浜轰綋鑲″渚х毊绁炵粡瑙e墫瀛﹀拰瓒呭0鎺㈡煡

銆€銆€鍏抽敭璇嶏細銆€鑲″渚х毊绁炵粡; 鎰熻寮傚父鎬ц偂鐥? 濉戝寲; 瓒呭0; 瑙e墫瀛? 浜?

銆€銆€Abstract锛氥€€Objective Meralgia paresthetica( MP) is commonly caused by mechanical entrapment of the lateral femoral cutaneous nerve( LFCN). The entrapment often occurs at the site where the nerve exits the pelvis. Its optimal surgical management remains to be established,partly because the fine architecture of the fascial planes around the lateral femoral cutaneous nerve has not been elucidated. The purpose of this study is to determine the fascia structure of lateral femoral cutaneous nerve nearby the anterior superior iliac spine using anatomy and ultrasound technique. Methods Eleven cadavers were selected for plastination( 6 female,5 male,age range 38-97 years). Ultrasonography was performed on 34 healthy volunteers( 19 women,15 men,age range,20-62 years). Results The lateral femoral cutaneous nerve exited the pelvis via a tendinous canal within the internal oblique-iliac fascia septum,and then between the sartorius muscle surface and the tensor fascia lata muscle located below the anterior superior iliac spine( ASIS). and then ran between the sartorius muscle and the tensor fascia. Conclusion Lateral femoral cutaneous nerve is located in the aponeurosis of the intraabdominal oblique muscle at the pelvic outlet. Lateral femoral cutaneous nerve travels on the surface and outside of the sartorius muscle. These two segments of lateral femoral cutaneous nerve can be localized by ultrasound scans.

銆€銆€Keyword锛氥€€Lateral femoral cutaneous nerve; Meralgia paresthetica; Sheet plastination; Ultrasound; Anatomy; Human;

銆€銆€鎰熻寮傚父鎬ц偂鐥?Meralgia paresthetica,MP)鏄竴绉嶅紩鍙戠柤鐥涳紝楹绘湪锛岀槞鐥掑拰鍓嶅渚уぇ鑵挎劅瑙夊紓甯哥殑绁炵粡绯荤粺鐤剧梾锛屼竴鑸槸鐢辫偂澶栦晶鐨缁?lateral femoral cutaneous nerve,LFCN)鐨勬満姊板祵鍘嬪紩璧穂1,2]銆傜洰鍓嶏紝閽堝MP鐨勬不鐤楀寘鎷繚瀹堟不鐤楀拰鎵嬫湳娌荤枟锛屾不鐤楃殑鍘熷垯鍜岀洰鐨勫潎鏄负浜嗙紦瑙FCN鍙楀帇锛屽噺杞荤浉鍏崇棁鐘躲€備繚瀹堟不鐤椾竴鑸€氳繃鐞嗙枟鍜岀缁忛樆婊為晣鐥?鎵嬫湳娌荤枟鍖呮嫭绠€鍗曞噺鍘嬶紝娴呰〃鍜屾繁灞傚噺鍘嬶紝楂傜瓔鑶滃垏鍙e噺鍘嬶紝鍐呬晶绉讳綅鍜?60°鍑忓帇[3,4,5,6,7,8]銆侻P璇婄枟鐨勫墠鎻愭槸鏄庣‘LFCN鐨勮В鍓栦綅缃拰姣楅偦缁撴瀯銆傜爺绌惰〃鏄庯紝LFCN鐨勮蛋琛屽瓨鍦ㄨВ鍓栧鍙樺紓锛屼絾鏈€甯歌鐨勮蛋琛屾槸缁忛珎鍓嶄笂妫?anterior superior iliac spine,ASIS)鍐呬晶杩涘叆澶ц吙鍖哄煙锛岄珎鍓嶄笂妫橀檮杩戝張鏄疞FCN鏈€甯歌鐨勫祵鍘嬮儴浣峓9]銆傜劧鑰岋紝鐢变簬鐩墠缂轰箯瀵筁FCN鍛ㄥ洿瑙e墫缁撴瀯鐨勭簿缁嗚瀵燂紝鐩稿叧娌荤枟鐨勬晥鐜囧拰娼滃湪鏈哄埗浠嶇劧鏈夊緟绮惧噯[4,5,6,7,8]銆傚洜姝わ紝鏄庣‘LFCN鍦ㄨ鍖哄煙鐨勭簿缁嗚В鍓栧彲浠ヤ负涓村簥娌荤枟MP鎻愪緵瑙e墫瀛︿緷鎹€?/span>

銆€銆€闅忕潃鍖荤枟褰卞儚鎶€鏈殑鍙戝睍锛岃秴澹版垚涓虹洰鍓嶄复搴婅瘖鐤桵P鐨勪富瑕佹妧鏈墜娈礫10]銆備絾LFCN缁撴瀯缁嗗皬锛屽湪瓒呭0涓嬭鍑嗙‘鍦拌瘑鍒叿鏈変竴瀹氱殑闅惧害銆傝В鍓栧鍙樺紓鐨勫瓨鍦紝鏇村鍔犱簡瓒呭0璇嗗埆鐨勯毦搴11]銆傚洜姝わ紝瓒呭0涓嬪浣曞揩閫熷噯纭湴璇嗗埆LFCN鑷冲叧閲嶈銆侲llis绛塠12]鍦ㄨВ鍓栧鍩虹涓婂埄鐢ㄨ秴澹板揩閫熺簿鍑嗗畾浣峀FCN锛屾彁楂樹簡鏈腑杈ㄨLFCN鐨勫噯纭€э紝鍑忓皯浜嗘墜鏈椂闂淬€傚浗鍐呯浉鍏宠В鍓栧鐮旂┒涓昏鏄繍鐢ㄥ眬閮ㄨВ鍓栬瀵烲FCN鐨勮蛋褰㈠彉寮傚拰鐩稿叧姣楅偦缁撴瀯锛屽鍞愪妇鐜夌瓑[13]灏哃FCN鐨勮蛋褰㈠垎涓烘櫘閫?鏀瀷銆侀珮浣嶅悗鏀瀷銆佸悗鏀己濡傚瀷銆佸墠鏀己濡傚瀷銆佺氦缁嗗瀷鍜岀己濡傚瀷銆傚紶瀹濆簡绛塠14]閫氳繃灞€閮ㄨВ鍓栧拰娴嬮噺瑙傚療浜哃FCN鐨勯绾ょ淮绠$殑鐩稿叧瑙e墫锛屽彂鐜癓FCN楠ㄧ氦缁寸鍑哄叆鍙g浉姣旓紝鍏ュ彛鐩村緞澶т簬鍑哄彛鐩村緞;涓旈绾ょ淮绠″叆鍙h窛绂籄SIS杈冭繙鑰屽懆鍥寸粨鏋勮緝鏉?鍑哄彛璺滱SIS杈冭繎锛屽懆鍥寸粨鏋勮緝鑷村瘑锛岄獙璇佷簡ASIS澶勪负LFCN鐨勬槗宓屽帇閮ㄤ綅銆備絾鏄紝灞€閮ㄨВ鍓栧绮剧粏绁炵粡鍙婂懆鍥寸瓔鑶滅殑瑙傚療鍏锋湁涓€瀹氱殑灞€闄愩€傚浗鍐呭叧浜嶭FCN鍦ˋSIS澶勭殑瓒呭0鐮旂┒椴滄湁鎶ラ亾锛屽垬鑺崇瓑[15]杩愮敤瓒呭0鍦ㄩ様绛嬭啘寮犺倢鍜岀紳鍖犺倢涔嬮棿瀹氫綅LFCN锛屼絾璇ュ尯鍩熷苟闈濴FCN鐨勬槗鍙楀祵鍘嬮儴浣嶃€傛湰鐮旂┒鎷熼噰鐢ㄨ杽灞傜敓鐗╁鍖栨妧鏈粨鍚堝仴搴峰織鎰胯€呰秴澹版鏌ワ紝瀵筁FCN杩涜瑙e墫瀛﹀拰瓒呭0瑙傚療锛屼互鏈熶负涓村簥MP鐨勮瘖鐤楁彁渚涗緷鎹€?/span>

銆€銆€璧勬枡鍜屾柟娉?/span>

銆€銆€鎴戜滑鍏辩爺绌朵簡11鍏峰案浣?6鍚嶅コ鎬э紝5鍚嶇敺鎬э紝骞撮緞鑼冨洿38锝?7宀?鍜?4鍚嶅仴搴峰織鎰胯€?19鍚嶅コ鎬э紝15鍚嶇敺鎬э紝骞撮緞鑼冨洿20锝?2宀?銆傚織鎰胯€呭潎鏃犱换浣曞ぇ鑵挎垨楠ㄧ泦鎹熶激鍙叉垨鎵嬫湳鍙层€傛湰鐮旂┒鏍规嵁濂ュ鍝ュぇ瀛﹀埗搴︿鸡鐞嗘寚鍗?institutional ethical guidelines of Otago University)杩涜锛屽苟鑾峰緱瀹夊窘鍖荤澶у浼︾悊濮斿憳浼氬拰濂ュ鍝ュぇ瀛?the institutional ethics committee of Otago University)鎵瑰噯銆?/span>

銆€銆€1锛庣敓鐗╁鍖栧垏鐗?/span>

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銆€銆€浣跨敤瑗块棬瀛怉cuon Antares鏈哄櫒(Siemens Medical Solutions)鍜岃タ闂ㄥ瓙vfx13-5绾挎€ц秴澹版帰澶磋幏寰楄秴澹板浘鍍忋€傚織鎰胯€呭彇浠板崸浣嶏紝澶ц吙浼哥洿锛岃剼灏栨湞涓婏紝灏嗚秴澹版帰澶存í鍚戞斁缃湪ASIS澶栦晶杩滅澶勶紝棣栧厛鏄剧ず闃旂瓔鑶滃紶鑲屽拰缂濆尃鑲岀殑妯柇闈€傚皢楂傚墠涓婃銆佽吂鍐呮枩鑲屽拰鑵瑰鏂滆倢銆佺紳鍖犺倢鍜岄様绛嬭啘寮犺倢浣滀负璇嗗埆鍜岃拷韪狶FCN鐨勬爣蹇椼€?/span>

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銆€銆€鎴戜滑鏀堕泦浜?1鍏峰案浣撳拰34浣嶅織鎰胯€呯殑璧勬枡骞跺垎鏋愭€荤粨鐗瑰緛銆傚洜涓哄睘浜庡畾鎬х爺绌讹紝鑰岄潪瀹氶噺鐮旂┒锛屾墍浠ユ湭瀵规墍鏈夊案浣撳拰蹇楁効鑰呯殑鐮旂┒缁撴灉琛ㄨ堪銆傚洜涓虹爺绌剁粨鏋滃叿鏈変竴鑷存€э紝鏁呴€夊彇浜嗕唬琛ㄦ€у浘鐗囨敹褰曞湪璇ヨ鏂囦腑浠ヨ〃杩扮爺绌剁粨鏋溿€?/span>

銆€銆€1锛庣敓鐗╁鍖栧垏鐗囩粨鏋?/span>

銆€銆€鍦ㄩ鐩嗗唴锛孡FCN浣嶄簬楂傜瓔鑶滃悗鏂广€侺FCN鍦ˋSIS鍐呬晶锛屽厛鍒虹┛楂傜瓔鑶滃苟杩涘叆楂傜瓔鑶滀笌鑵瑰唴鏂滆倢鑵辫啘绾ょ淮涔嬮棿(鍥?A)锛岀劧鍚嶭FCN缁х画璧拌绌胯繃鑵瑰唴鏂滆倢鑵辫啘绾ょ淮锛岃蛋琛屼簬鑵瑰鏂滆倢鐨勮叡鑶滀笅渚у嚭楠ㄧ泦銆傚湪ASIS鐨勪笅鏂癸紝鑵瑰鏂滆倢鑵辫啘鐨勬祬琛ㄧ氦缁村欢浼稿埌澶ц吙杩滅骞惰瀺鍏ラ様绛嬭啘銆侺FCN鍑洪鐩嗗悗鏂滆法鑷崇紳鍖犺倢澶栦晶鍚庤蛋琛屼簬涓ゅ眰闃旂瓔鑶滀腑闂?鍥?B)銆?/span>

銆€銆€2锛庤秴澹版帰娴嬬粨鏋?/span>

銆€銆€璇勪及浜?4鍚嶅織鎰胯€呴鐩嗗嚭鍙eLFCN璧板悜鐨勮繃绋嬨€傚湪楠ㄧ泦鍐咃紝LFCN鍦ㄩ珎鑲屽墠鏂圭殑楂樺洖澹板唴璧拌銆傞珮鍥炲0鍦ㄨ吂鍐呮枩鑲屽渚у叿鏈夋槑鏄剧殑寤剁画锛屽苟鍦ㄨ吂澶栨枩鑲岃叡鑶滀笅渚фí鍚戞眹鍏SIS(鍥?A)銆傚湪姘村钩浣嶅浘涓婏紝闃旂瓔鑶滃紶鑲屽拰缂濆尃鑲岀殑鑲岄棿闅欏憟浣庡洖澹帮紝鍦ㄤ綆鍥炲0鍐呯殑LFCN鐨勭煭杞村憟鍏稿瀷鐨勫嵉鍦嗗舰缁撴瀯锛屽懆鍥寸殑绁炵粡澶栬啘琛ㄧ幇涓洪珮鍥炲0锛岄儴鍒哃FCN鍙樉绀哄涓缁忔潫锛屽憟绛涚綉鏍风粨鏋?鍥?B)銆侺FCN鍦ˋSIS浣嶇疆绌垮嚭楠ㄧ泦锛屽湪缂濆尃鑲屽渚у拰闃旂瓔鑶滃悗鏂硅繘鍏ュぇ鑵胯繙绔?鍥?B)銆?/span>

銆€銆€璁ㄨ

銆€銆€LFCN鏉ユ簮浜庣2銆?鑵扮缁忓墠鏀悗娈电殑绾劅瑙夌缁忥紝鍦ㄨ叞澶ц倢鍚庢柟涓嬭锛屾枩鍚戝涓嬫柟绌胯叞澶ц倢鑷冲叾澶栦晶缂橈紝缁忛珎鑲屽墠鏂硅繎ASIS澶勭寮€楠ㄧ泦锛岃繘鍏ュぇ鑵垮墠澶栦晶鍒嗘敮寤朵几鍚戣偄浣撹繙绔€傝櫧鐒禠FCN鍦ˋSIS闄勮繎鐨勮В鍓栧缁撴瀯鍙婂叾鍙樺紓宸茬粡鏈夊箍娉涚殑鐮旂┒锛屼絾鏅亶璁や负锛孡FCN鍦ㄨ吂鑲℃矡闊у甫涓嬫垨绌胯繃鑵硅偂娌熼煣甯﹀嚭楠ㄧ泦銆傛牸寮忚В鍓栧鎸囧嚭锛岃吂鑲℃矡闊у甫涓鸿吂澶栨枩鑲岃叡鑶滃湪ASIS澶勫弽鎶樹笅闄峰舰鎴愮殑鍦嗗舰杈圭紭锛屽苟鍚戜笅寤朵几涓虹瓔鑶溿€傞珎绛嬭啘鍜岃吂鍐呮枩鑲岃叡鑶滃湪鑵硅偂娌熼煣甯﹀拰楂嬮涔嬮棿褰㈡垚1涓叡鍚岀殑闅旇啘(鎴栭珎鑰荤)锛岃闅旇啘浣嶄簬鑵瑰鏂滆倢鍚庢柟锛屽叡鍚岄檮鐫€鍦ㄩ珎楠ㄥ拰鑵硅偂娌熼煣甯︿笂銆傚湪楠ㄧ泦鍐咃紝LFCN浣嶄簬楂傜瓔鑶滅殑鍚庢柟锛岃绁炵粡璧拌鑷矨SIS鍐呬晶闄勮繎鍖哄煙鏃跺埡绌块珎绛嬭啘鍜岃吂鍐呮枩鑲岃叡鑶滃舰鎴愮殑闅旇啘鍚庯紝璧拌鍦ㄩ珎绛嬭啘鍜岃吂鍐呮枩鑲岃叡鑶滀袱鑰呬箣闂村苟涓斿舰鎴愬畬鏁寸殑绛嬭啘闉樺寘瑁筁FCN銆傚洜姝わ紝LFCN蹇呴』鍒虹┛鑵瑰唴鏂滆倢-楂傜瓔鑶滈殧鑶滄墠鑳藉嚭楠ㄧ泦銆傜爺绌惰〃鏄庯紝璇ョ瓔鑶滈灅浣嶄簬鑵瑰鏂滆倢鑵辫啘绾ょ淮鐨勬繁閮ㄥ拰鍐呴儴锛岀敱鑵瑰唴鏂滆倢鑵辫啘绾ょ淮缁勬垚銆侺FCN鍒虹┛鑵瑰唴鏂滆倢-楂傜瓔鑶滈殧鑶滃悗琚吂鍐呮枩鑲岃叡鑶滅氦缁村寘瑁规垚瀹屾暣绛嬭啘闉橈紝甯镐笌楂傞様闊у甫铻嶅悎(鍥?A)锛岀劧鍚庡嚭楠ㄧ泦杩涘叆鑵瑰鏂滆倢鑵辫啘涓嬩晶锛屽湪缂濆尃鑲屽渚у悜澶ц吙杩滅璧拌銆?/span>

銆€銆€鏈爺绌惰〃鏄庯紝璇ョ瓔鑶滈灅鏄敱鑵瑰唴鏂滆倢鍜岄珎绛嬭啘鐨勭氦缁寸幆缁曞舰鎴愩€傞櫎鑵瑰唴鏂滆倢澶栵紝楂傜瓔鑶滀篃閫氳繃鑵规í鑲岃叡鑶滃姞寮恒€傚洜姝わ紝鑵归儴鑲岃倝(鐗瑰埆鏄吂鍐呮枩鑲屽拰鑵规í鑲?鐨勬媺浼稿彲鑳戒細鏀剁揣鍜岀缉灏廘FCN鐨勭瓔鑶滈灅锛屽LFCN鐨勬満姊板祵鍘嬫湁鏄剧潃褰卞搷銆?/span>

銆€銆€鍥? LFCN鍦ˋSIS鍖哄煙妯柇闈㈠鍖栧垏鐗囨爣灏虹ず10 mm
鍥? LFCN鍦ˋSIS鍖哄煙妯柇闈㈠鍖栧垏鐗囨爣灏虹ず10 mm

銆€銆€Fig.1 Two transverse plastinated sections at the levels of the ASIS Bar=10 mm

銆€銆€A.LFCN鍦ˋSIS姘村钩浣嶇疆璧拌;B锛庡湪ASIS姘村钩浣嶇疆浠ヤ笅LFCN鍑洪鐩嗚蛋琛岃繘鍏ヨ剛鑲;榛戣壊绠ご涓洪珎绛嬭啘;绾㈣壊铏氱嚎鍦堝唴涓篖FCN;a锛庡墠渚?m锛庡唴渚?ASIS锛庨珎鍓嶄笂妫?IF锛庨珎绛嬭啘;IP锛庨珎鑵拌倢;Sar锛庣紳鍖犺倢;TFL锛庨様绛嬭啘寮犺倢;RF锛庤偂鐩磋倢;GMi锛庤噣灏忚倢

銆€銆€A,LFCN traveled at horizontal position of ASIS;B,LFCN exited the pelvis and traveled into the adipose compartment below the level of ASIS;The black arrow is the iliac fascia;The red dotted line is LFCN;the crossed arrows indicate the orientation;a,Anterior;m,Medial;ASIS,Anterior superior iliac spine;IF,Iliac fascia;IP,Iliopsoas muscle;Sar,Sartorius muscle;TFL,Tensor fasciae latae;RF,Rectus femoris;GMi,Gluteus minimus

銆€銆€鍥? 瓒呭0鍥惧儚鏍囧昂绀?0 mm
鍥? 瓒呭0鍥惧儚鏍囧昂绀?0 mm

銆€銆€Fig.2 Ultrasound images Bar=10 mm

銆€銆€A锛庡湪ASIS姘村钩浣嶇疆锛孡FCN鍒虹┛楂傜瓔鑶?鑵瑰唴鏂滆倢鑵辫啘绠″悗璧拌鍦ㄨ吂澶栨枩鑲岃叡鑶滅氦缁翠笅灞?B锛庡湪ASIS姘村钩浣嶇疆浠ヤ笅锛孡FCN杩涘叆鑴傝偑瀹よ蛋琛屽湪缂濆尃鑲屽拰闃旂瓔鑶滃紶鑲岃〃闈?绾㈣壊铏氱嚎鍦堝唴涓篖FCN;鐧借壊闀跨澶翠负楂傞様闊у甫;鐧借壊绠ご涓篖FCN绛嬭啘闉?ASIS锛庨珎鍓嶄笂妫?IOA锛庤吂鍐呮枩鑲?EOA锛庤吂澶栨枩鑲?IP锛庨珎鑵拌倢;RF锛庤偂鐩磋倢;TFL锛庨様绛嬭啘寮犺倢;Sar锛庣紳鍖犺倢

銆€銆€A,At the ASIS level,LFCN pierced the tendinous canal of the iliac fascia and the aponeurotic fibers of the internal oblique abdominis and traversed within the aponeurotic fibers of the external oblique abdominis;B,Below the level of ASIS,LFCN traveled into the adipose compartment,which is on the surface of the sartorius muscle and the tensor fasciae latae;ASIS,Anterior superior iliac spine;IOA,Internal oblique abdominis;EOA,External oblique abdominis;IP,Iliopsoas muscle;RF,Rectus femoris;TFL,Tensor fasciae latae;Sar,Sartorius muscle

銆€銆€LFCN鐨勮秴澹板畾浣嶄富瑕佸湪缂濆尃鑲屼笂鏂瑰拰LFCN鐨勭瓔鑶滈灅[7,12,16,17]銆侶anna[18]閫氳繃妯悜瓒呭0鍥惧儚璇佸疄浜哃FCN琚氦缁村寘瑁瑰舰鎴愬畬鏁寸殑绛嬭啘闉樸€傝绛嬭啘闉樹娇寰桳FCN鍦ㄨ秴澹板奖鍍忓浘涓婃洿鍔犲鏄撹杈╄瘑(鍥?B)锛岄檷浣庝簡瓒呭0杈ㄥ埆鐨勯毦搴︼紝鎻愰珮浜哃FCN瓒呭0瀹氫綅鐨勬晥鐜囥€傜敱浜嶭FCN鍦ㄩ鐩嗗唴浣嶄簬楂傜瓔鑶滃拰鑵瑰唴鏂滆倢涔嬮棿锛岀粡ASIS鍑洪鐩嗘椂浣嶄簬鑵瑰鏂滆倢涓嬩晶銆傛湰鐮旂┒鍒╃敤鑵瑰唴鏂滆倢銆佽吂澶栨枩鑲屻€佺紳鍖犺倢鍜孉SIS浣滀负鏍囪锛屽璇ラ儴浣嶈繘琛屼簡瓒呭0璇勪及銆傚皢瓒呭0鎺㈠ご姘村钩鏀剧疆鍦ˋSIS涓婏紝瓒呭0褰卞儚鏄剧ず涓洪珮鍥炲0褰?鍥?A)锛屽湪楠ㄧ泦鍐咃紝鍙竻鏅拌娴嬪埌LFCN宸插埡绌胯吂鍐呮枩鑲岃叡鑶滐紝璧拌鍦ㄨ吂澶栨枩鑲岃叡鑶滀笅渚с€傝鍖哄煙鏄竴涓檮鐫€鍦ˋSIS涓婃柟鐨?銆?灞傜獥甯樼姸缁撴瀯鐨勭瓔鑶滃眰锛屼笌闃旂瓔鑶滃唴澶栦晶浜ょ粐锛屽苟妯悜寤剁画涓虹毊闊у甫鍥哄畾鍦ㄧ毊鑲や笂銆侻ing绛塠19]閫氳繃鍏辩劍鎶€鏈拰涓夌淮閲嶅缓锛屽皢璇ョ瓔鑶滅粨鏋勫畾涔変负楂傞様闊у甫(鍥?A鐧借壊绠ご鎸囩ず)銆傞珎闃旈煣甯︾殑瀛樺湪澧炲姞浜哃FCN瓒呭0涓嬭京璇嗙殑闅惧害锛孡FCN鍦ㄧ┛鑵瑰唴鏂滆倢鍜岃吂澶栨枩鑲屽嚭楠ㄧ泦鏃讹紝LFCN鐨勭瓔鑶滈灅甯镐笌楂傞様闊у甫浜ょ粐锛屽湪瓒呭0鏄惧奖涓婇毦浜庤鲸璁ゃ€傚洜姝わ紝鍦ㄩ€氳繃LFCN鍦ˋSIS闄勮繎鍑洪鐩嗘椂鐨勮蛋鍚戝強鍏跺懆鍥寸簿缁嗙粨鏋勪簡瑙g殑鍩虹涓婏紝鏈爺绌跺缓璁紝鍦ㄨ秴澹版帰娴婰FCN鏃讹紝灏嗚秴澹版帰澶存按骞虫斁缃簬ASIS涓婏紝鍒╃敤鑵瑰唴鏂滆倢鍜岃吂澶栨枩鑲岋紝楂傞様闊у甫鐨勭粨鏋勭壒鐐规帰娴婰FCN(鍥?A)銆傝嫢LFCN鍦ㄥ嚭楠ㄧ泦鏃惰瀺鍏ラ珎闃旈煣甯﹀唴涓嶆槗杈╄瘑锛屽垯灏嗘帰澶寸◢鍚戜笅澶栦晶绉诲姩锛屾帰娴嬪埌缂濆尃鑲屽拰闃旂瓔鑶滃紶鑲屻€侺FCN鍑洪鐩嗗悗璧拌鍦ㄧ紳鍖犺倢鍜岄様绛嬭啘寮犺倢琛ㄩ潰锛岃秴澹板奖鍍忓浘鏄剧ず锛孡FCN鍦ㄧ紳鍖犺倢鍜岄様绛嬭啘寮犺倢涓婃柟鐨勪袱灞傞珎绛嬭啘涔嬮棿锛屽苟琚畬鏁寸殑绛嬭啘闉樺寘瑁?鍥?B)銆?/span>

銆€銆€鎴戜滑璇佸疄浜哃FCN鍦ˋSIS闄勮繎浣嶄簬鑵瑰唴鏂滆倢鑵辫啘鍐咃紝鑵瑰唴鏂滆倢-楂傜瓔鑶滆唸鑶滃拰LFCN绛嬭啘闉樹娇鍏舵槗鍙桝SIS闄勮繎鏈烘宓屽帇銆侺FCN鍦ㄩ鐩嗗嚭鍙e瑙e墫瀛︾爺绌跺拰瓒呭0瀹氫綅锛屼负涓村簥鎵嬫湳鎻愪緵浜嗘湁鍒╃殑渚濇嵁銆?/span>

銆€銆€鍙傝€冩枃鐚?/span>

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銆€銆€鍘熸枃鍑哄锛氶┈鏅撴収,閮戣█瑷€,寰愭湞闃?寮犻摥,寰愯儨鏄?鑲″渚х毊绁炵粡鍦ㄩ珎鍓嶄笂妫橀檮杩戠殑瑙e墫瀛﹀拰瓒呭0瑙傚療[J].瑙e墫瀛︽姤,2020,51(03):416-419.
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