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閲嶇棁鏀師浣撹偤鐐庢偅鍎垮簲鐢ㄤ笝绉嶇悆铔嬬櫧鐨勬晥鏋滃垎鏋?/h1>

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纭?a href="http://flywand.com/" style="text-decoration-line: none; font-size: 12px; color: rgb(51, 51, 51);">鍗氳鏂囩綉鏄竴瀹朵笓涓氭彁渚涜鏂囧畾鍒朵慨鏀规湇鍔$殑缃戠珯锛屼笂10骞寸殑璁烘枃缁忛獙锛屾棤璁烘槸鏈璁烘枃銆佺澹鏂囪繕鏄湡鍒婅鏂囷紝鍗氬+璁烘枃锛屾垜浠兘鑳戒负鎮ㄦ彁渚涙柟渚裤€佸揩鎹枫€佸畨鍏ㄧ殑璁烘枃鏈嶅姟銆備互涓嬫槸纭曞崥璁烘枃缃戝皬缂栦负鎮ㄧ簿蹇冩寫閫夌殑涓€绡囧尰瀛﹁鏂囨瘯涓?a href="http://flywand.com/index.php?upcache=1" style="text-decoration-line: none; font-size: 12px; color: rgb(51, 51, 51);">璁烘枃鑼冩枃锛屽唴瀹规槸鍏充簬閲嶇棁鏀師浣撹偤鐐庢偅鍎垮簲鐢ㄤ笝绉嶇悆铔嬬櫧鐨勬晥鏋滃垎鏋?strong style="color: rgb(0, 0, 0); font-family: 寰蒋闆呴粦; font-size: 16px;">銆傛湰鏂?/strong>缁撹 涓欑鐞冭泲鐧借仈鍚堝父瑙勬不鐤楁柟妗堝鍎跨閲嶇棁鏀師浣撹偤鐐庣枟鏁堟洿浣?鍙湁鏁堜績杩涙偅鍎夸复搴婄棁鐘舵仮澶?缂╃煭鐥呯▼,鏀瑰杽棰勫悗銆傚浜庡効绔ラ噸鐥囨敮鍘熶綋鑲虹値鍦ㄥ父瑙勫ぇ鐜唴閰被鎶楃敓绱犳不鐤楀熀纭€涓?鑱斿悎浣跨敤涓欑鐞冭泲鐧藉彲鎶戝埗鐐庣棁鍙嶅簲,鎻愰珮涓村簥鐤楁晥,缂╃煭鐥呯▼,鏀瑰杽棰勫悗,鍊煎緱涓村簥鎺ㄥ箍浣跨敤銆備互渚涘弬鑰冦€備互渚涘悇浣嶅悓瀛﹀弬鑰冿紝甯屾湜瀵瑰ぇ瀹舵湁鎵€甯姪銆?/strong>

銆€鎽?nbsp;   瑕侊細銆€鐩殑 鎺㈣涓欑鐞冭泲鐧芥不鐤楀効绔ラ噸鐥囨敮鍘熶綋鑲虹値鐨勪复搴婄枟鏁堛€傛柟娉?鏍规嵁娌荤枟鏂规鐨勪笉鍚?灏?0渚嬮噸鐥囪偤鐐庢敮鍘熶綋鑲虹値鎮e効鍒嗕负瑙傚療缁勫拰瀵圭収缁?姣忕粍40渚嬨€傚鐓х粍缁欎簣闃垮闇夌礌绛夊父瑙勬不鐤?瑙傚療缁勭粰浜堜笝绉嶇悆铔嬬櫧+甯歌娌荤枟,姣旇緝涓ょ粍鎮e効鐑€€鏃堕棿銆佸挸鍡芥秷澶辨椂闂淬€佽兏閮–T鐐庣棁鍚告敹鏃堕棿銆丆鍙嶅簲铔嬬櫧(CRP)鍙奃-浜岃仛浣撱€佷钩閰歌劚姘㈤叾(LDH)姘村钩銆傜粨鏋?娌荤枟7澶╁悗,瑙傚療缁勬€绘湁鏁堢巼楂樹簬瀵圭収缁?P<0.05)銆傝瀵熺粍鎮e効鐨勯€€鐑椂闂寸煭浜庡鐓х粍(P<0.05)銆傝瀵熺粍鍜冲椊娑堝け鏃堕棿鍜岃兏閮–T鐐庣棁鍚告敹鏃堕棿鍧囩煭浜庡鐓х粍(P<0.05)銆傝瀵熺粍CRP,D-浜岃仛浣撱€丩DH姘村钩鍧囦綆浜庡鐓х粍(P<0.05)銆傜粨璁?涓欑鐞冭泲鐧借仈鍚堝父瑙勬不鐤楁柟妗堝鍎跨閲嶇棁鏀師浣撹偤鐐庣枟鏁堟洿浣?鍙湁鏁堜績杩涙偅鍎夸复搴婄棁鐘舵仮澶?缂╃煭鐥呯▼,鏀瑰杽棰勫悗銆?/span>

閲嶇棁鏀師浣撹偤鐐庢偅鍎垮簲鐢ㄤ笝绉嶇悆铔嬬櫧鐨勬晥鏋滃垎鏋? src=

銆€銆€鍏抽敭璇嶏細銆€鏀師浣撹偤鐐? 鍎跨; 涓欑鐞冭泲鐧? 涓村簥鐤楁晥;

銆€銆€Abstract锛氥€€Objective To explore the clinical effect of gamma globulin on children with severe mycoplasma pneumonia. Methods According to different treatment schemes, 80 cases of severe mycoplasma pneumonia were divided into observation group and control group, 40 cases in each group. The control group was given routine treatment such as azithromycin, and the observation group was given gamma globulin + routine treatment. The time of fever regression, cough disappearance, chest CT inflammation absorption time, C-reactive protein(CRP), D-dimer and lactate dehydrogenase(LDH) levels were compared between two groups. Results After 7 days of treatment, the total efficiency of observation group was higher than that of control group(P<0.05). The time of fever regression in observation group was shorter than that in control group(P<0.05). The time of cough disappearance and chest CT inflammation absorption time of observation group were shorter than those of control group(P<0.05). The levels of CRP, D-dimer and LDH in observation group were lower than those in control group(P<0.05). Conclusion Gamma globulin combined with routine treatment schemes has better effect on children with severe mycoplasma pneumonia, which can effectively promote the recovery of clinical symptoms in children, shorten the course of disease and improve prognosis.

銆€銆€Keyword锛氥€€mycoplasma pneumonia; children; gamma globulin; clinical efficacy;

銆€銆€鏍规嵁鍥藉唴璧勬枡鏄剧ず,鏀師浣撹偤鐐庡湪鍎跨绀惧尯鑾峰緱鎬ц偤鐐庨珮鍙戞湡鍗?0%浠ヤ笂,闈為珮鍙戞湡鍗?0%锝?0%[1]銆傛敮鍘熶綋鑲虹値鍙戠梾鐜囧崰绀惧尯鑾峰緱鎬ц偤鐐庡彂鐥呯巼鐨勪竴鍗婂乏鍙?骞朵笖鍙戠梾鐜囨鍦ㄩ€愬勾澧炲姞[2]銆備互寰€鏀師浣撹偤鐐庤璁や负鏄竴绉嶈嚜闄愭€х柧鐥?鍏朵复搴婄壒鐐逛负:鎸佺画鍙戠儹,鍓х儓鍜冲椊,鑲洪儴浣撳緛杞诲井浠ュ強棰勫悗鑹ソ銆備絾杩戝勾鏉?涓村簥涓婂嚭鐜颁簡瓒婃潵瓒婂鐨勯毦娌绘€ц偤鐐?涓嶄粎琛ㄧ幇涓哄懠鍚搁亾鐥囩姸,杩樹即鏈夊绉嶈偤澶栧苟鍙戠棁,涓ラ噸濞佽儊鍎跨鐨勫仴搴穂3]銆傛湰鐮旂┒瑙傚療涓欑鐞冭泲鐧芥不鐤楀効绔ラ噸鐥囨敮鍘熶綋鑲虹値鐨勭枟鏁?鐜板皢缁撴灉鎶ラ亾濡備笅銆?/span>

銆€銆€1 銆佽祫鏂欎笌鏂规硶

銆€銆€1.1銆?鐥呬緥閫夋嫨

銆€銆€閫夊彇2015骞?鏈堣嚦2018骞?鏈堝攼灞卞競濡囧辜淇濆仴闄㈠皬鍎垮懠鍚哥鏀舵不鐨勯噸鐥囨敮鍘熶綋鑲虹値鎮e効80渚嬨€傛牴鎹不鐤楁柟妗堢殑涓嶅悓,闅忔満鍒嗕负瑙傚療缁勫拰瀵圭収缁?姣忕粍40渚嬨€傝瀵熺粍鐢?3渚?濂?7渚?骞冲潎骞撮緞(5.93±2.54)宀?鍏ラ櫌鍓嶅钩鍧囩梾绋?6.12±1.73)澶?鑳搁儴CT鏀瑰彉涓哄弻渚ц偤鐐?2渚?鍗曚晶鑲虹値28渚?鑳歌厰绉恫22渚?瀵圭収缁勭敺25渚?濂?5渚?骞冲潎骞撮緞(6.26±2.34)宀?鍏ラ櫌鍓嶅钩鍧囩梾绋?6.23±1.82)澶?鑳搁儴CT鏀瑰彉涓哄弻渚ц偤鐐?3渚?鍗曚晶鑲虹値27渚?鑳歌厰绉恫21渚嬨€備袱缁勬€у埆銆佸勾榫勩€佺梾绋嬬瓑涓€鑸祫鏂欐瘮杈冨樊寮傛棤缁熻瀛︽剰涔夈€?/span>

銆€銆€1.2 銆佸叆閫夋爣鍑?/span>

銆€銆€绾冲叆鏍囧噯:骞撮緞2锝?2宀?涓村簥璧勬枡瀹屾暣銆傚湪璇婃柇鏀師浣撹偤鐐庡悗,濡傛灉鍙戠幇鏈変互涓嬪墠3涓爣鍑嗕腑鐨?涓拰(鎴?鍚庝袱涓爣鍑嗕腑鐨?涓?鍒欏彲璇婃柇涓洪噸鐥囨敮鍘熶綋鑲虹値[4]:鈶犲懠鍚哥煭淇冩垨蹇冨姩杩囬€?浼存湁鎴栦笉浼存湁琛€鍘嬩笅闄嶃€佸彛鍛ㄥ彂缁€鍜屼笁鍑瑰緛闃虫€х瓑;鈶℃湁鏁堝簲鐢ㄥぇ鐜唴閰被鎶楃敓绱犳不鐤楄秴杩噇鍛?浣撴俯浠嶆寔缁?gt;38.5 鈩?鎴栬偤閮ㄥ奖鍍忓鏃犳敼鍠勬垨杩涘睍,鎴栨槸鍙戠儹鏃堕棿>10澶?鈶㈣偤閮ㄥ奖鍍忓妫€鏌ユ樉绀洪珮瀵嗗害鐥呭彉,绱強涓€涓偤娈靛拰澶氫釜鑲哄彾;鈶e彂鐢熻偤鍧忔銆佽偤鑴撹偪銆佽偤涓嶅紶鎴栬€呰兏鑵旂Н娑茬瓑鑳歌厰鍐呭悎骞剁棁;鈶や綆姘ц鐥?鍦ㄥ惛鍏ョ┖姘旀潯浠朵笅,鍔ㄨ剦姘у垎鍘?lt;60 mmHg(1 mmHg=0.133 kPa); 鎴栧嚭鐜板叾浠栫郴缁熶弗閲嶅悎骞剁棁銆傛帓闄ゆ爣鍑?浼存湁蹇冭剰,鑲濊剰,鑲捐剰绛夐噸瑕佽剰鍣ㄥ熀纭€鐤剧梾鐨勬偅鍎?浼存湁鑲洪棿璐ㄧ柧鐥呫€佹敮姘旂鍝枠绛夋參鎬у懠鍚哥郴缁熺柧鐥呯殑鎮e効;浼存湁鍏堝ぉ鎬у厤鐤柧鐥呮垨姝d娇鐢ㄥ厤鐤姂鍒跺墏鐨勬偅鍎裤€?/span>

銆€銆€1.3 銆佹不鐤楁柟娉?/span>

銆€銆€涓ょ粍鎮e効鍧囩粰浜堥潤鑴夋敞灏勭敤闃垮闇夌礌(灞变笢缃楁鑽笟闆嗗洟鑲′唤鏈夐檺鍏徃,鍥借嵂鍑咹20066405,瑙勬牸:0.125 g) 10 mg/kg闈欒剦婊存敞,1娆?d,杩炵敤5澶╁悗鍋滅敤3澶?鐢插熀寮虹殑鏉鹃緳(杈夌憺鍒惰嵂鏈夐檺鍏徃,鍥借嵂鍑嗗瓧:H20080284,瑙勬牸:40 mg)1 mg/(kg·娆?,2娆?d;鍚屾椂瀵规偅鍎胯繘琛岄檷娓┿€佺鐥板拰姝㈠挸绛夊鐥囨不鐤?瑙傚療缁勯櫎甯歌娌荤枟鏂规澶栫粰浜堜笝绉嶇悆铔嬬櫧400 mg/(kg·d),杩炵敤3澶?闈欐敞浜哄厤鐤悆铔嬬櫧(pH4)(涓婃捣鑾卞+琛€娑插埗鍝佽偂浠芥湁闄愬叕鍙?鍥借嵂鍑嗗瓧S10980061,瑙勬牸:50 ml:2.5 g)銆?/span>

銆€銆€1.4銆?璇勪环鎸囨爣

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銆€銆€1.5 銆佺粺璁″鏂规硶

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琛? 涓ょ粍涓村簥鐤楁晥姣旇緝[渚?%)]

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銆€銆€琛? 涓ょ粍鐥囩姸鏀瑰杽鎯呭喌姣旇緝(x?±s,d)

琛? 涓ょ粍鐥囩姸鏀瑰杽鎯呭喌姣旇緝(x?卤s,d)

銆€銆€2.3銆?涓ょ粍CRP銆丏-浜岃仛浣撳強LDH姣旇緝

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銆€銆€琛? 涓ょ粍CRP銆丏-浜岃仛浣撳強LDH姣旇緝(x?±s)

琛? 涓ょ粍CRP銆丏-浜岃仛浣撳強LDH姣旇緝(x?卤s)

銆€銆€娉?涓庢不鐤楀墠姣旇緝,*P<0.05

銆€銆€3銆?璁?璁?/span>

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銆€銆€[1] 楂樺瓱濞?闄堣堪鑻?鏉ㄦ檽闆?鍎跨鑲虹値鏀師浣撴劅鏌撶殑娴佽鐥呭鐗瑰緛鍒嗘瀽[J].娉板北鍖诲闄㈠鎶?2018,39(4):385-387.
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銆€銆€鍘熸枃鍑哄锛氶粍鍏変妇,寮犳収鐜?鏉庡,鏉庝匠.涓欑鐞冭泲鐧芥不鐤楀効绔ラ噸鐥囨敮鍘熶綋鑲虹値鐨勪复搴婄枟鏁圼J].涓村簥鑽熻悆,2020,35(08):732-735.

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